Prevention of thrombotic complications in patients with myocardial infarction, ischemic stroke or peripheral artery occlusion. In combination with acetylsalicylic acid (ASA) for the prevention of thrombotic complications in acute coronary syndrome: with ST segment elevation when thrombolytic therapy is possible; without ST segment elevation (unstable angina or myocardial infarction without Q wave), including in patients undergoing stenting.
Hypersensitivity to the active or any auxiliary component of the drug. Lactose intolerance, lactase deficiency, and glucose-galactose malabsorption syndrome. Age up to 18 years (efficacy and safety of use have not been established). Severe liver failure. Acute bleeding (including peptic ulcer or intracranial hemorrhage). Pregnancy and lactation.